(There’s a reason I write skincare blog posts and not, say, songs). Chemically modified vitamin molecules are more stable, and pure vitamin is released from the derivatives inside the body. Related: Is Jar Packaging A Waste Of Money? UNII-47143LT58A. :) You are almost done: please check your mailbox to confirm your email! So great in fact, that it surpasses the penetration of pure vitamin C threefold at the same concentration and it penetrates successfully into the deeper layers of the skin (that is usually important to do some anti-aging work). In addition, vitamin C's three magic properties (antioxidant, collagen booster, skin brightener) are all properly proven in-vivo (on real people), but for the derivatives, it's mostly in-vitro studies or in the case of ATIP, it's in-vitro and done by an ingredient supplier. 47143LT58A. l-ascorbic acid, tetrakis(2-hexyldecanoate) EC 430-110-8. Ascorbyl Tetraisopalmitate is one of the most powerful forms of Vitamin C to fade away wrinkles and dark spots. The Ordinary Ascorbyl Tetraisopalmitate Solution 20% In Vitamin F (£14.90): available at Asos, Beauty Bay, Cult Beauty and Sephora; Zelens Power C High Potency Vitamin C Treatment Drops (£125.00): available at Cult Beauty and Barneys; SHOP THE POST. The study was a small (10 patients), double-blind experiment, and the formula did show some measurable anti-aging results. Oristar THA. However, it is hard to know how much pure vitamin C or ATIP can be thanked. Well, I tried. Ascorbyl tetraisopalmitate (Tetrahexyldecyl Ascorbate) is a molecule derived from vitamin C and isopalmitic acid. It is one of the most stable derivatives of Vitamin C but, being a derivative, its potency will not be directly comparable to pure L-Ascorbic Acid. So now, you know that Vitamin C is great and all, but it's really unstable and gives cosmetics companies many headaches. FutureDerm is committed to having its customers find — and create — the best skin care for their individual skin type, concern, and based on your ingredient preferences. Form of Vitamin C, Ascorbyl Isotetrapalmitate, Ascorbyl Tetraisopalmitate, ATIP. Vitamin C is an effective antioxidant, brightens the skin tone and reduces signs of aging. There is also in-vitro data showing that it converts to AA in the skin. What Are The Best Products With Tetrahexyldecyl Ascorbate? 15% Vitamin C Brightening Serum, VI Aesthetics Vi Derm Vitamin C Brightening Concentrate, A'KIN Certified Organic Rosehip Oil with Vitamin C, Basiclab Antyoksydacyjne Serum Regenerujące Odżywienie Wyrównanie 10%, Basiclab Serum Z Witaminą C 5% Odżywienie Wygładzenie, Colleen Rothschild Vitamin C Treatment Complex, DR. LEWINN'S Reversaderm Collagen Accelerator Serum, Dr. Jetske Ultee Moisturizer for normal and dry skin, Ghost Democracy Lightbulb Vitamin C Serum, Journal of Cosmetic Dermatology, Volume 11 (4) – Dec 1, 2012, Stability, transdermal penetration, and cutaneous effects of ascorbic acid and its derivatives, Dermatologic Surgery, Mar 1, 2002, Double‐Blind, Half‐Face Study Comparing Topical Vitamin C and Vehicle for Rejuvenation of Photodamage, Barnet Products Corp, Stable forms of Vitamin C, Technical Bulletin, 2001. It is a clinically proven, stable, oil-soluble vitamin C derivative that provides superior percutaneous absorption and effectively converts to free vitamin C in the skin. If you are looking for a form of vitamin C that is both stabilized and fast-acting, look no further: Ascorbyl tetraisopalmitate has been shown to be absorbed into the skin more quickly than other forms of vitamin C. However, the downside to ascorbyl tetraisopalmitate may be that it is so fast-acting it may be irritating for sensitive skin. BV-OSC. We are massive vitamin C fans and have written about it in excruciating detail. Vitamin C tetra-isopalmitate. The purpose of this blog is for skin care-related reviews and tips only. ascorbyl tetraisopalmitate. Truth Treatment Systems Resurfacing 1% Retinol Light, Essano Advanced Brightening Vitamin C Concentrated Serum, INSTYTUTUM Anti-Wrinkle Brightening C-Erum, Kate Somerville Kx Active Concentrates Vitamin B3 + Vitamin C, MZ Skin Brighten & Perfect 10% Vitamin C Corrective Serum, MooGoo Ascorbyl Tetraisopalmitate (Vitamin C) In Squalane, Perricone MD High Potency Classics Firming Eye Lift, Perricone MD Vitamin C Ester Brightening Overnight Treatment, Perricone MD Vitamin C Ester Brightening Serum, Peter Thomas Roth Potent C Targeted Spot Brightener, Revision Skincare C+ Correcting Complex 30%, Sunday Riley C.E.O. Learn more by visiting the FutureDerm shop! I think somebody should make a song about all of the different forms of vitamin C. Like a vitamin C jingle: L-ascorbic acid is the first and stays in the skin at any rate. Ascorbyl Tetraisopalmitate (ATIP) is the tetraester of ascorbic acid and isopalmitic acid. Topical use can mitigate the damaging effects of UV exposure. NIKKOL VC-IP. The heat and humidity of the bath helps key ingredients and moisture to lock into the skin, whereas the ingredients have been shown in studies to be brightening and tightening for the skin. 183476-82-6. If you have sensitive skin, the citrus extracts may be too much. Tetrahexyldecyl Ascorbate is a stable, oil-soluble form of skincare big shot Vitamin C. If you do not know, why Vitamin C is such a big deal in skincare, click here and read all about it. Aside from that benefit, it appears to have similar collagen-rebuilding properties to other forms of vitamin C, as shown in its ability to increase UVA/UVB photoprotection and to aid in the healing of burns (Photochemistry and Photobiology, 2008; Burns, 2010; International Journal of Pharmaceutics, 2007). However, as you know from my constant musings on the benefits of microencapsulation, offering slow release of ingredients into the skin, sometimes you don’t want for ingredients to be mega-dosed into the skin or quickly absorbed all at once. Ascorbyl tetraisopalmitate (also tetra-isopalmitoyl ascorbate, or Tetrahexyldecyl Ascorbate) is a molecule derived from vitamin C. It is produced by combining one molecule of vitamin C (ascorbic acid) with four molecules of tetraisopalmitic acid, a fatty acid found in butter and other sources. Perfect-C™ (Ascorbyl Tetraisopalmitate) ... INCI: Ascorbyl Tetraisopalmitate หรือ Tetrahexyldecyl Ascorbate. Ascorbyl glucosamine has more lightening properties (ooo). Sodium ascorbyl phosphate and Magnesium ascorbyl palmitate are more stable than ascorbyl palmitate (AP), so AP is out-of-date. 20.0% | Ascorbyl Tetraisopalmitate Solution 20% In Vitamin F, 10.0% | Vitamin C 35% Collagen Rebuilding Serum, 10.0% | Ideal Resource Renewing Pro-Vitamin C And E Oil Concentrate, 3.0% | Refreshing Brightening Serum (2020). The authors theorized that the 10% AA is released slowly from the silicon delivery system and probably stays in the upper layer of the skin to give antioxidant benefits, while ATIP penetrates more rapidly and deeply and gives some wrinkle-reducing benefits. Some researchers believe this form of vitamin C has a greater affinity for skin because its fatty acid component helps aid penetration. Ascorbyl tetra-2-hexyldecanoate. But if you’re looking for big-time action from your vitamin C and have resilient skin, ascorbyl tetraisopalmitate may be just the ticket. But Tetrahexyldecyl Ascorbate will last you a lot longer even if not kept under lock and key. For this reason, it makes sense that ascorbyl tetraisopalmitate is associated with some irritation (contact dermatitis) in persons with sensitive skin (Contact Dermatitis, 2011). As far as benefits go, as I’ve said before on the blog, you need to apply a cleanser for at least a minute in order to ensure that all of the beneficial ingredients can be absorbed into the skin properly. So this all sounds really great, but these are only in-vitro results at this point. Looking for the best skin care? These 4 ingredients, Tetrahexyldecyl Ascorbate, Ascorbyl Isostearate, Ascorbyl Linoleate, and Ascorbyl Tetraisopalmitate, are being reviewed for the first time in this safety assessment. Nikkol BV-OSC. 2,3,5,6-O-Tetra-2'-hexyldecanoyl-L-ascorbic acid. We could find Tetrahexyldecyl Ascorbate mentioned only in one published in-vivo study that examined the anti-aging properties of a silicone formula containing 10% AA and 7% ATIP. Looking for the best skin care? Vitamin C-isopalmityl tetraester. Please try again later! Tetrahexyldecyl Ascorbate is stable at a pH of <5 so don’t worry too much if the packaging is see-through. We could find Tetrahexyldecyl Ascorbate mentioned only in one published in-vivo study that examined the anti-aging properties of a silicone formula containing 10% AA and 7% ATIP. With this context in mind let's see what ATIP might be able to do. Unlike pure vitamin C (ascorbic acid), tetrahexyldecyl ascorbate is lipid (fat) soluble. Tetrahexyldecyl ascorbate also known as Ascorbyl Tetraisopalmitate, is an oil-soluble derivative of vitamin C. Unlike other Vitamin C derivatives that are water-soluble and can’t pass through the skin barrier, tetrahexyldecyl ascorbate penetrates the dermis and epidermis stimulating collagen production. I personally recommend using Ole Henriksen Pure Truth Melting Cleanser when taking a bath, if you do not have sensitive skin. I still prefer tubes over jars because, hygiene. It’s the other side of the coin: if Ascorbyl Tetraisopalmitate can penetrate skin more deeply and deliver a more powerful dose of Vitamin C, it makes sense it’s also more likley to irritate your skin. FutureDerm is committed to having its customers find — and create — the best skin care for their individual skin type, concern, and based on your ingredient preferences. Second, because it's oil-soluble, its skin penetration abilities seem to be great. Thanks. Tetrahexyldecyl Ascorbate oder auch Ascorbyl Tetraisopalmitate (TETRA) ist ein relativ neues, öllösliches Vitamin C-Derivat. First, it is stable (if pH < 5), easy to formulate and a joy to work with for a cosmetic chemist. Learn more by visiting the, Ole Henriksen Pure Truth Melting Cleanser. Ascorbyl Tetraisopalmitate may be the exception. Studies have shown it can irritate sensitive skin. The Bottom Line . Tetrahexyldecyl Ascorbate is a very stable, oil-soluble Vitamin C ester which has anti-oxidant activity, inhibiting lipid peroxidation. It is not intended as and does not substitute for medical advice. A molecule derived from vitamin C and isopalmitic acid, ascorbyl tetraisopalmitate has been shown to absorb into skin faster than any of the other forms of vitamin C tested (Clinics in Dermatology, 2008). Pure vitamin C has several drawbacks for cosmeceutical use, most important of which is the low stability. Posts are not intended to diagnose, treat, or cure disease. SCHEMBL16541147 Information posted should not be construed as personal medical advice. Third, ATIP seems to have all three magic abilities of pure vitamin C: it gives antioxidant protection from both UVB and UVA rays, it increases collagen synthesis (even more than AA) and it has a skin brightening effect by reducing melanogenesis by more than 80% in human melanoma cell cultures. Ascorbyl glucoside is vitamin C plus a sugar (baby). Ascorbyl Tetraisopalmitate is an oil-soluble derivative of Vitamin C that can be used in higher concentrations without drawbacks. Tetrahexyldecyl ascorbate absorbs into skin the best. Bottom line: a really promising, but not well-proven vitamin C derivative that can be worth a try especially if you like experimenting (but if you like the tried and true, pure vitamin C will be your best bet). To solve this problem they came up with vitamin C derivatives, and one of them is Tetrahexyldecyl Ascorbate (let's call it ATIP in short). 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