Zetia Muscle Pain – Myalgia, Myopathy & Rhabdomyolosis . Your healthcare provider can discuss a more complete list of Zetia side effects with you.) Our Zetia Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. So, some people think this drug may have effects to gain weight. Until that, it’s better to be aware of keeping in mind about the risk. Common Side Effects of Zetia. Avoid alcohol after taking this drug. Read More. You may report side effects to FDA at 1-800-FDA-1088. Symptoms reported are Myalgia and myopathy. I too have had to resort to Zetia after side effects with all the others. I have had very good results following the diet in the Digest Diet book, put out by Reader's Digest. SIDE EFFECTS FOR ZETIA: COMMENTS: SEX: AGE: DURATION/ DOSAGE: DATE ADDED : 1: Elevated LDL cholesterol: Headaches. otherwise, it will hurt you. Call your doctor for medical advice about side effects. Zetia Muscle pain is one among of its side effects. Upset stomach, backache, pain in knee joint, fatigue, nasal congestion. This bloatedness can cause for pseudo weight gain as well. There are many good drugs on the market which may not give you such severe side effects. In these studies, side effects are always documented and compared to another group not taking the medicine. A natural alternative for lowering LDL cholesterol may be a much safer option for you and is worth exploring with your cardiologist. I Have used Generic Zetia 10 mg. there are no side effects. This is not a complete list of side effects and others may occur. Hence, let’s wait until the experts announce whether this can cause weight gain and by that for diabetes. Find information about common, infrequent and rare side effects of Zetia Oral. However, this fact is still under research. Zetia (ezetimibe) is a drug used in the treatment of high-cholesterol. 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